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When there's a lower probability of embryo fertilization with IVF, intracytoplasmic sperm injection (ICSI) may be used, where a single sperm is injected directly into each of the eggs. 

When is 

ICSI used?

  • When men have compromised sperm, like low concentration, motility, morphology, or anti-sperm antibodies

  • Blockage or absence of the vas deferens, where sperm is surgically collected by epididymal aspiration or testicular biopsy

  • If you've had low or failed fertilization on prior IVF attempts

  • In cases of unexplained infertility (where infertility cause remains unknown after diagnostic testing)

  • Where certain medication or other medical history cause a problem with sperm

  • IVF cycles involving pre-implantation genetic diagnosis/screening